A recent study emphasises grapes' ability to offer photoprotection.
It has been demonstrated by a recent study in the journal Antioxidants that eating grapes can help prevent skin damage from UV rays. Two weeks of daily consumption of two and a half cups of grapes boosted study participants' resilience to sunburn. Due to the fact that those subjects who had UV resistance also had distinctive microbiomic and metabolomic profiles, the study also discovered a potential link between the gut and skin. According to the study, grapes' naturally occurring polyphenols may be the cause of these beneficial effects.
The results of this new study support earlier studies in this field. Researchers tested the effects of ingesting whole grape powder, which is equivalent to 2 14 cups of grapes each day, on photodamage from UV light in this study on 29 human volunteers. Using the minimal erythema dose, which is the threshold level of UV radiation that causes visible reddening within 24 hours, researchers were able to compare the skin reaction of subjects to UV light before and after they had consumed grapes for two weeks (MED). Additionally, the gut microbiome, blood, and urine samples underwent metabolomic analysis.
After consuming grapes, one-third of the patients showed UV resistance, and these same individuals showed notable alterations in their microbiome and metabolome compared to the non-responders. Notably, the UV-resistant group had decreased levels of the same three urine metabolites. A particular metabolite, 2'-deoxyribose, is a potent marker of decreased photodamage and reveals distinct genetic profiles relevant to customised therapy.
In addition, three of the UV-resistant patients demonstrated a long-lasting reaction, meaning that their UV protection persisted even after going back to not eating any grapes for another four weeks. According to this research, there is a link between the gut-skin axis and UV tolerance, and some people can withstand sunburns after consuming grapes.
Each year, skin cancer affects over 3 million Americans, mostly as a result of sun exposure. By the time they turn 70, one in five Americans will have skin cancer. About 90% of nonmelanoma skin cancer cases and 86 percent of melanomas, respectively, are linked to sun exposure and skin cancer. In addition, the sun is thought to be responsible for 90 percent of skin ageing.
Lead author John Pezzuto, a professor and dean at Western New England University in Springfield, Massachusetts, adds that Hippocrates is credited with coining the phrase "Let thy food be thy medicine and medicine be thy food." We are still learning the truth of this statement even after 2500 years, as demonstrated by this human study using dietary grapes.
Short-Term Grape Consumption Reduces UV-Induced Skin Erythema, 30 November 2022, Antioxidants, John M. Pezzuto, Asim Dave, Eun-Jung Park, Diren Beyolu, and Jeffrey R. Idle.
Reference: 10.3390/antiox11122372
The California Table Grape Commission provided funding for this study. The choice to submit the work for publication, as well as the gathering, analysing, and interpretation of data, were not made with the involvement of the funder.
0 Comments